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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
HIRA
All Species:
21.21
Human Site:
S627
Identified Species:
29.17
UniProt:
P54198
Number Species:
16
Phosphosite Substitution
Charge Score:
-0.06
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P54198
NP_003316.3
1017
111835
S627
L
A
K
A
S
S
L
S
K
R
K
L
E
L
E
Chimpanzee
Pan troglodytes
XP_001165585
1017
111787
S627
L
A
K
A
S
S
L
S
K
R
K
L
E
L
E
Rhesus Macaque
Macaca mulatta
XP_001112873
1138
124408
S748
L
A
K
P
S
S
L
S
K
R
K
L
E
L
E
Dog
Lupus familis
XP_543550
1017
111618
S627
V
T
K
P
S
S
L
S
K
R
K
L
E
L
E
Cat
Felis silvestris
Mouse
Mus musculus
Q61666
1015
111748
S625
L
A
K
P
S
S
L
S
K
R
K
L
E
L
E
Rat
Rattus norvegicus
NP_001129232
1015
111665
S625
L
A
K
P
S
S
L
S
K
R
K
L
E
L
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
P79987
1019
112055
P633
A
A
K
P
L
S
A
P
K
R
K
L
E
L
E
Frog
Xenopus laevis
Q8QFR2
1013
112021
K623
P
A
S
K
Q
L
S
K
R
K
G
E
A
D
A
Zebra Danio
Brachydanio rerio
XP_696478
1010
111223
K620
N
K
T
L
S
M
A
K
R
K
G
E
I
E
G
Tiger Blowfish
Takifugu rubipres
O42611
1025
111838
A635
P
E
L
L
M
D
G
A
E
V
V
E
K
R
K
Fruit Fly
Dros. melanogaster
O17468
1047
113397
H645
S
L
T
S
S
A
V
H
C
A
F
S
P
D
N
Honey Bee
Apis mellifera
XP_001122939
838
91355
Q466
R
T
P
T
F
T
S
Q
V
K
S
S
I
V
I
Nematode Worm
Caenorhab. elegans
Q09589
935
103412
A563
T
T
S
Q
P
M
L
A
L
D
L
K
K
P
A
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Q32SG6
964
105548
L592
S
L
T
P
C
S
A
L
S
I
H
V
I
N
K
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9LXN4
1051
115544
V648
S
D
R
I
M
G
R
V
T
V
L
A
G
N
P
Baker's Yeast
Sacchar. cerevisiae
P32479
840
93871
E468
D
A
S
V
S
R
S
E
H
I
N
I
L
I
P
Red Bread Mold
Neurospora crassa
Q7RZI0
1035
112420
V626
P
N
I
A
Y
S
Q
V
R
L
A
V
P
K
I
Conservation
Percent
Protein Identity:
100
99.9
88.4
96.5
N.A.
95.7
95.5
N.A.
N.A.
86
78
69.8
67.7
31.1
40
26.5
N.A.
Protein Similarity:
100
99.9
88.9
98
N.A.
97.5
97.7
N.A.
N.A.
93.1
88.5
83.2
81.3
48
55.1
46.1
N.A.
P-Site Identity:
100
100
93.3
80
N.A.
93.3
93.3
N.A.
N.A.
66.6
6.6
6.6
0
6.6
0
6.6
N.A.
P-Site Similarity:
100
100
93.3
86.6
N.A.
93.3
93.3
N.A.
N.A.
66.6
20
20
26.6
26.6
20
20
N.A.
Percent
Protein Identity:
N.A.
25.6
N.A.
25
22.4
25.9
Protein Similarity:
N.A.
43.7
N.A.
43.3
41.2
45.8
P-Site Identity:
N.A.
6.6
N.A.
0
13.3
13.3
P-Site Similarity:
N.A.
20
N.A.
6.6
26.6
26.6
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
6
48
0
18
0
6
18
12
0
6
6
6
6
0
12
% A
% Cys:
0
0
0
0
6
0
0
0
6
0
0
0
0
0
0
% C
% Asp:
6
6
0
0
0
6
0
0
0
6
0
0
0
12
0
% D
% Glu:
0
6
0
0
0
0
0
6
6
0
0
18
42
6
42
% E
% Phe:
0
0
0
0
6
0
0
0
0
0
6
0
0
0
0
% F
% Gly:
0
0
0
0
0
6
6
0
0
0
12
0
6
0
6
% G
% His:
0
0
0
0
0
0
0
6
6
0
6
0
0
0
0
% H
% Ile:
0
0
6
6
0
0
0
0
0
12
0
6
18
6
12
% I
% Lys:
0
6
42
6
0
0
0
12
42
18
42
6
12
6
12
% K
% Leu:
30
12
6
12
6
6
42
6
6
6
12
42
6
42
0
% L
% Met:
0
0
0
0
12
12
0
0
0
0
0
0
0
0
0
% M
% Asn:
6
6
0
0
0
0
0
0
0
0
6
0
0
12
6
% N
% Pro:
18
0
6
36
6
0
0
6
0
0
0
0
12
6
12
% P
% Gln:
0
0
0
6
6
0
6
6
0
0
0
0
0
0
0
% Q
% Arg:
6
0
6
0
0
6
6
0
18
42
0
0
0
6
0
% R
% Ser:
18
0
18
6
53
53
18
36
6
0
6
12
0
0
0
% S
% Thr:
6
18
18
6
0
6
0
0
6
0
0
0
0
0
0
% T
% Val:
6
0
0
6
0
0
6
12
6
12
6
12
0
6
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
6
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _